A papilloma is a benign epithelial tumor type, which causes projections on the skin-shaped papillae or warts. Often is associated with human papillomavirus.
It is generally very difficult to completely eradicate the infection and therefore in most cases treatment to reduce or eliminate the damage caused by HPV. As the infection underlying injury remains, is the frequent occurrence of relapses and should keep medical monitoring.
Most methods have good results and there is no further data that point to a preferred procedure, nor information on the comparative effectiveness of monotherapy and combined treatments, so the therapeutic approach is left to the discretion of the physician and the patient.
• Topical agents - On injury, promote the dissolution of keratin and / or death of the cells that constitute the lesion. Ex: podophyllin, 5-fluorouracil, trichloroacetic acid.
• Immunomodulators - substances that stimulate the immune system fight infection. Ex: imiquimod, retinoids, interferon.
• Surgical procedures - removal of lesions through various processes, for example, excision with a scalpel, high-frequency surgery, laser therapy and cryotherapy.
Prognosis
The cutaneous lesions (warts) are generally not of concern from the standpoint of clinical status. The main complication is associated with progression to cancer lesions caused by certain types of HPV, especially in the cervix. The lesions observed by cytology or biopsy are categorized into three stages, ranging from CIN-I (mild dysplasia)-CIN III (carcinoma in situ''''), which has a high probability of invasive cervical cancer progresses to. A greater extent of dysplasia carries a worse prognosis, so the sooner it is diagnosed, the better are the chances that injuries are controlled with treatment. It is very unlikely that after diagnosis and early treatment dysplasia developing into cancer.
In immunocompromised patients, the risk of progression to cancer is high due to low responsiveness against the offending agent as well as the decreased ability to detect and destroy infected cells.
The results of a Pap smear may often indicate the presence of atypical cells (ASCUS, English undertemined atypical cells of significance). As the name implies, these atypical cells do not have a clear meaning, but are an indication to increase the level of preventive vigilance.
It is generally very difficult to completely eradicate the infection and therefore in most cases treatment to reduce or eliminate the damage caused by HPV. As the infection underlying injury remains, is the frequent occurrence of relapses and should keep medical monitoring.
Most methods have good results and there is no further data that point to a preferred procedure, nor information on the comparative effectiveness of monotherapy and combined treatments, so the therapeutic approach is left to the discretion of the physician and the patient.
• Topical agents - On injury, promote the dissolution of keratin and / or death of the cells that constitute the lesion. Ex: podophyllin, 5-fluorouracil, trichloroacetic acid.
• Immunomodulators - substances that stimulate the immune system fight infection. Ex: imiquimod, retinoids, interferon.
• Surgical procedures - removal of lesions through various processes, for example, excision with a scalpel, high-frequency surgery, laser therapy and cryotherapy.
Prognosis
The cutaneous lesions (warts) are generally not of concern from the standpoint of clinical status. The main complication is associated with progression to cancer lesions caused by certain types of HPV, especially in the cervix. The lesions observed by cytology or biopsy are categorized into three stages, ranging from CIN-I (mild dysplasia)-CIN III (carcinoma in situ''''), which has a high probability of invasive cervical cancer progresses to. A greater extent of dysplasia carries a worse prognosis, so the sooner it is diagnosed, the better are the chances that injuries are controlled with treatment. It is very unlikely that after diagnosis and early treatment dysplasia developing into cancer.
In immunocompromised patients, the risk of progression to cancer is high due to low responsiveness against the offending agent as well as the decreased ability to detect and destroy infected cells.
The results of a Pap smear may often indicate the presence of atypical cells (ASCUS, English undertemined atypical cells of significance). As the name implies, these atypical cells do not have a clear meaning, but are an indication to increase the level of preventive vigilance.
Nenhum comentário:
Postar um comentário