quinta-feira, 11 de julho de 2013

Felty's syndrome

Felty's syndrome is the triad of rheumatoid arthritis, neutropenia (neutrophil count decreased blood) and splenomegaly (enlarged spleen).
No word yet on the cause of this syndrome, however, is more common in individuals who have had rheumatoid arthritis for a long time (affects approximately 1% of patients). This syndrome most commonly affects individuals between 50 to 70 years of age, and two thirds of patients are female.

Prevention and Treatment
Clinical manifestations include:
• Unwillingness;
• Fatigue;
• Loss of appetite;
• Weight loss;
• Pallor;
• Stiffness, pain, deformity and joint inflammation;
• Recurrent infections, due to low neutrophil count;
• Burning sensation in the eyes and / or eye discharge.
Closes the diagnosis when these three conditions are present: low neutrophil count (evidenced peloexame up blood), rheumatoid arthritis (diagnosed by physical examination) and splenomegaly (confirmed through an abdominal ultrasound).

There is no cure for this disease. Treatment for patients with this syndrome generally aims to control rheumatoid arthritis and may require immunosuppressive drugs. Splenectomy may lead to improvement of severe neutropenia.

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